Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses

Fungi are a source of natural bioactive compounds that offer therapeutic potential in the prevention of viral diseases and for the improvement of human immunomodulation. Here, we made a brief review of the current findings on fungi as producers of protease inhibitors and studies on the relevant candidate fungal bioactive compounds that can offer immunomodulatory activities as potential therapeutic agents of coronaviruses in the future.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221821/

Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles

Although it is common practice to apply the originally European name ‘Ganoderma lucidum’ to all commerical reishi products. Taxonomists have made a case that there is a difference between East Asian strains G. lingzhi and the European G. lucidum strains. G. lucidum contains less triterpenic acids than G. lingzhi.
https://www.sciencedirect.com/science/article/pii/S0031942216300413

Radioprotective Effect of Ganoderma lucidum (Leyss, ex. Fr.) Karst after X-ray Irradiation in Mice

Hsue-Yin Hsu – School of Technology for Medical Sciences, Kaohsiung Medical College, Kaohsiung, Taiwan

Shi-Long Lian – Department of Radiotherapy, Kaohsiung Medical College, Kaohsiung, Taiwan

Chun-Ching Lin – School of Pharmacy, Kaohsiung Medical College, Kaohsiung, Taiwan

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