Fungi are a source of natural bioactive compounds that offer therapeutic potential in the prevention of viral diseases and for the improvement of human immunomodulation. Here, we made a brief review of the current findings on fungi as producers of protease inhibitors and studies on the relevant candidate fungal bioactive compounds that can offer immunomodulatory activities as potential therapeutic agents of coronaviruses in the future.
Although it is common practice to apply the originally European name ‘Ganoderma lucidum’ to all commerical reishi products. Taxonomists have made a case that there is a difference between East Asian strains G. lingzhi and the European G. lucidum strains. G. lucidum contains less triterpenic acids than G. lingzhi.