The Pharmacological Rationales and Molecular Mechanisms of Ganoderma lucidum Polysaccharides for the Therapeutic ApplicatiHua Luo (*Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China), Dechao Tan (*Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory… Continue reading The Pharmacological Rationales and Molecular Mechanisms of Ganoderma lucidum Polysaccharides for the Therapeutic Applications of Multiple Diseases
Category: Research
Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview
Cör Andrejč D, Knez Ž, Knez Marevci M. Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. PMID: 35935849; PMCID: PMC9353308. Abstract Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of… Continue reading Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview
The medicinal mushroom Ganoderma lucidum attenuates UV-induced skin carcinogenesis and immunosuppression
Shahid A, Huang M, Liu M, Shamim MA, Parsa C, et al. (2022) The medicinal mushroom Ganoderma lucidum attenuates UV-induced skin carcinogenesis and immunosuppression. PLOS ONE 17(3): e0265615. https://doi.org/10.1371/journal.pone.0265615 Abstract The medicinal mushroom Ganoderma lucidum is traditionally used for treating multiple diseases, including cancer. This study examined skin cancer preventive activity of a commercial product containing spore and fruiting body in 30:8 ratio (GLSF). Extracts of… Continue reading The medicinal mushroom Ganoderma lucidum attenuates UV-induced skin carcinogenesis and immunosuppression
Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats
Tian B, Zhao Q, Xing H, Xu J, Li Z, Zhu H, Yang K, Sun P, Cai M. Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats. Nutrients. 2022; 14(7):1476. https://doi.org/10.3390/nu14071476 Abstract Ganoderma lucidum is known as a medicine food homology that can ameliorate gastrointestinal diseases. To evaluate the gastroprotective effects… Continue reading Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
Jan JT, Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2021 Feb… Continue reading Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses
Suwannarach, N., Kumla, J., Sujarit, K., Pattananandecha, T., Saenjum, C., & Lumyong, S. (2020). Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses. Molecules (Basel, Switzerland), 25(8), 1800. https://doi.org/10.3390/molecules25081800 Abstract The inhibition of viral protease is an important target in antiviral drug discovery and development. To date, protease inhibitor… Continue reading Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses
Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective
Yang, Y., Islam, M. S., Wang, J., Li, Y., & Chen, X. (2020). Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective. International journal of biological sciences, 16(10), 1708–1717. https://doi.org/10.7150/ijbs.45538 Abstract Currently, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, formerly known as 2019-nCoV, the causative pathogen of Coronavirus Disease… Continue reading Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective
Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles
Florian Hennicke, Zakaria Cheikh-Ali, Tim Liebisch, Jose G. Maciá-Vicente, Helge B. Bode, Meike Piepenbring, Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles, Phytochemistry, Volume 127, 2016, Pages 29-37, ISSN 0031-9422, https://doi.org/10.1016/j.phytochem.2016.03.012. Abstract In China and other countries of East… Continue reading Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles
Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., & Guo, G. (2017). Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells. Oncology letters, 14(6), 7467–7472. https://doi.org/10.3892/ol.2017.7153 Abstract Ganoderma lucidum, within the Polyporaceae family of Basidiomycota, is a popular traditional remedy medicine used in Asia to promote health and longevity. Compounds extracted from G. lucidum have revealed… Continue reading Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells
Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology
Guggenheim, A. G., Wright, K. M., & Zwickey, H. L. (2014). Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integrative medicine (Encinitas, Calif.), 13(1), 32–44. Abstract This review discusses the immunological roles of 5 major mushrooms in oncology: Agaricus blazei, Cordyceps sinensis, Grifola frondosa, Ganoderma lucidum, and Trametes versicolor. These mushrooms were selected based on the body of research performed on… Continue reading Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology